中文名稱: TPX2 抗原(重組蛋白)
英文名稱: TPX2 Antigen (Recombinant Protein)
別 名: TPX2, microtubule-associated; DIL2; p100; DIL-2; HCTP4; FLS353; HCA519; REPP86; C20orf1; C20orf2; GD:C20orf1
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別:抗原
概 述
Full name: |
TPX2, microtubule-associated |
Synonyms: |
DIL2; p100; DIL-2; HCTP4; FLS353; HCA519; REPP86; C20orf1; C20orf2; GD:C20orf1 |
Swissprot: |
Q9ULW0 |
Gene Accession: |
BC004136 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
TPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 for the chromatin-induced microbutule assembly during M phase. Aurora-A kinase associates with TPX2 at the spindle apparatus and may regulate TPX2 via phosphorylation during the spindle assembly. TPX2 appears to play a structural role in spindle formation. TPX2 activates Eg2 in a microtubule-dependent manner by stimulating the phosphorylation and kinase activity of Eg2. |