中文名稱:ACVR1C 抗原(重組蛋白)
英文名稱: ACVR1C Antigen (Recombinant Protein)
別 名: activin A receptor, type IC; ALK7; ACVRLK7
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 195-485 amino acids of human ACVR1C |
Full name: |
activin A receptor, type IC |
Synonyms: |
ALK7; ACVRLK7 |
Swissprot: |
Q8NER5 |
Gene Accession: |
BC022530 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]). |