中文名稱: UACA 抗原(重組蛋白)
英文名稱: UACA Antigen (Recombinant Protein)
別 名: uveal autoantigen with coiled-coil domains and ankyrin repeats; NUCLING
儲 存: 冷凍(-20℃)
相關(guān)類別:抗原
概 述
Full name: |
uveal autoantigen with coiled-coil domains and ankyrin repeats |
Synonyms: |
NUCLING |
Swissprot: |
Q9BZF9 |
Gene Accession: |
BC113407 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity). |