兔抗DNMT3A多克隆抗體

Background:

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.

Applications:

ELISA, IHC

Name of antibody:

DNMT3A

Immunogen:

Fusion protein of human DNMT3A

Full name:

DNA (cytosine-5-)-methyltransferase 3 alpha

Synonyms：

DNMT3A2; M.HsaIIIA

SwissProt:

Q9Y6K1

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and human thyroid cancer

IHC Recommend dilution:

50-200