技術(shù)規(guī)格
Background: |
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. |
Applications: |
ELISA, IHC |
Name of antibody: |
KCNIP3 |
Immunogen: |
Fusion protein of human KCNIP3 |
Full name: |
potassium voltage-gated channel interacting protein 3 |
Synonyms: |
CSEN; DREAM; KCHIP3 |
SwissProt: |
Q9Y2W7 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human brain |
IHC Recommend dilution: |
50-100 |