兔抗MNT多克隆抗體

Background:

The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.

Applications:

WB

Name of antibody:

MNT

Immunogen:

Synthesized peptide derived from internal of human MNT.

Full name:

MAX network transcriptional repressor

Synonyms：

ROX; MAD6; MXD6; bHLHd3

SwissProt:

Q99583

WB Predicted band size:

62 kDa

WB Positive control:

A549 cells lysate

WB Recommended dilution:

500-3000