兔抗IKBKG(Ab-85) 多克隆抗體

Background:

This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

WB, IF

Name of antibody:

IKBKG(Ab-85)

Immunogen:

Synthesized non-phosphopeptide derived from human IKK-γ around the phosphorylation site of serine 85 (Q-A-S(p)-Q-R).

Full name:

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

Synonyms：

IP; IP1; IP2; FIP3; IPD2; NEMO; FIP-3; Fip3p; IMD33; AMCBX1; ZC2HC9; IKK-gamma

SwissProt:

Q9Y6K9

WB Predicted band size:

48 kDa

WB Positive control:

HepG2 cells treated with Anisomycin (0.5uM, 5hours) lysate

WB Recommended dilution:

500-3000

IF positive control:

Hela cells

IF Recommend dilution:

100-500