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  • 兔抗CRK多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW15684
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:75
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中文名稱(chēng):
兔抗CRK多克隆抗體


英文名稱(chēng): Anti-CRK rabbit polyclonal antibody

別      名: p38; CRKII

相關(guān)類(lèi)別: 一抗

抗      原: CRK

儲(chǔ)      存: 冷凍(-20℃)

宿      主: Rabbit

反應(yīng)種屬: Human, Mouse, Rat

標(biāo)  記 物: Unconjugate

克隆類(lèi)型: rabbit polyclonal

技術(shù)規(guī)格

Background:

This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.

Applications:

ELISA, IHC

Name of antibody:

CRK

Immunogen:

Fusion protein of human CRK

Full name:

v-crk avian sarcoma virus CT10 oncogene homolog

Synonyms:

p38; CRKII

SwissProt:

P46108

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human colon cancer

IHC Recommend dilution:

50-200