中文名稱:小鼠抗CHD4單克隆抗體
Background: |
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Applications: |
WB, IP |
Name of antibody: |
CHD4 |
Immunogen: |
Fusion protein of human CHD4 |
Full name: |
chromodomain helicase DNA binding protein 4 |
Synonyms: |
CHD-4; Mi-2b; SIHIWES; Mi2-BETA |
SwissProt: |
Q14839 |
WB Predicted band size: |
218 kDa |
WB Positive control: |
293, Jurkat, MOLT-4, HL-60, HelaNE and K562 cell lysates |
WB Recommended dilution: |
1000-5000 |