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中文名稱：兔抗CASP14多克隆抗體
英文名稱： Anti-CASP14 rabbit polyclonal antibody
相關(guān)類別： 一抗
抗 原： CASP14
儲 存： 冷凍（-20℃）
宿 主： Rabbit
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. |
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Applications: |
ELISA, WB |
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Name of antibody: |
CASP14 |
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Immunogen: |
Fusion protein of human CASP14 |
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Full name: |
caspase 14, apoptosis-related cysteine peptidase |
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SwissProt: |
P31944 |
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ELISA Recommended dilution: |
2000-5000 |
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WB Predicted band size: |
28 kDa |
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WB Positive control: |
Jurkat, A431, A549 and A375 cells |
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WB Recommended dilution: |
500-2000 |
