購物車
幫助
021-54845833/15800441009
別 名： BRI; FBD; ABRI; BRI2; E25B; E3-16; RDGCA; imBRI2; BRICD2B
抗 原： ITM2B
標(biāo) 記 物： Unconjugate
技術(shù)規(guī)格
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Background: |
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
ITM2B |
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Immunogen: |
Fusion protein of human ITM2B |
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Full name: |
integral membrane protein 2B |
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Synonyms: |
BRI; FBD; ABRI; BRI2; E25B; E3-16; RDGCA; imBRI2; BRICD2B |
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SwissProt: |
Q9Y287 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
30 kDa |
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WB Positive control: |
Rat kidney tissue lysate |
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WB Recommended dilution: |
500-2000 |
