兔抗TGFBR2多克隆抗體

Background:

This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors.

Applications:

WB

Name of antibody:

TGFBR2

Immunogen:

Synthesized peptide derived from human TGF β Receptor II antibody.

Full name:

transforming growth factor, beta receptor II (70/80kDa)

Synonyms：

AAT3; FAA3; LDS2; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TGFR-2; TGFbeta-RII

SwissProt:

P37173

WB Predicted band size:

65 kDa

WB Positive control:

HepG2 cells lysate

WB Recommended dilution:

500-3000