中文名稱: 兔抗PIM1多克隆抗體
英文名稱: Anti-PIM1 rabbit polyclonal antibody
別 名: PIM
相關(guān)類別: 一抗
儲(chǔ) 存: 冷凍(-20℃)
抗 原: PIM1
宿 主: Rabbit
反應(yīng)種屬: Human, Mouse, Rat
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons. |
Applications: |
ELISA, IHC |
Name of antibody: |
PIM1 |
Immunogen: |
Fusion protein of human PIM1 |
Full name: |
pim-1 oncogene |
Synonyms: |
PIM |
SwissProt: |
P11309 |
ELISA Recommended dilution: |
1000-5000 |
IHC positive control: |
Human liver cancer and human thyroid cancer |
IHC Recommend dilution: |
50-200 |