購(gòu)物車(chē)
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021-54845833/15800441009
中文名稱(chēng)：兔抗RPS6KA5(Phospho-Ser212) 多克隆抗體
英文名稱(chēng)： Anti-RPS6KA5(Phospho-Ser212) rabbit polyclonal antibody
別 名： MSK1; RLPK; MSPK1
抗 原： RPS6KA5(Phospho-Ser212)
儲(chǔ) 存： 冷凍（-20℃） 避光
宿 主： Rabbit
反應(yīng)種屬： Human Mouse
相關(guān)類(lèi)別： 一抗
標(biāo)記物： Unconjugate
克隆類(lèi)型： Unconjugate
技術(shù)規(guī)格
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Background: |
Serine/threonine kinase required for the mitogen or stress-induced phosphorylation of the transcription factors CREB (cAMP response element-binding protein) and ATF1 (activating transcription factor-1). Essential role in the control of RELA transcriptional activity in response to TNF. Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A. Phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and epidemal growth-factor (EGF), which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN. May also phosphorylate 'Ser-28' of histone H3. Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 14 (HMG-14). |
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Applications: |
WB |
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Name of antibody: |
RPS6KA5(Phospho-Ser212) |
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Immunogen: |
Peptide sequence around phosphorylation site of serine 212 (A-Y-S(p)-F-C) derived from Human MSK1. |
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Full name: |
ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
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Synonyms： |
MSK1; RLPK; MSPK1 |
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SwissProt: |
O75582 |
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WB Predicted band size: |
90 kDa |
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WB Positive control: |
NIH/3T3 cells lysates treated with EGF |
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WB Recommended dilution: |
500-1000 |
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