英文名稱: UBE2B Antigen (Recombinant Protein)
別 名: HR6B; UBC2; HHR6B; RAD6B; E2-17kDa
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述
Full name: |
ubiquitin-conjugating enzyme E2B |
Synonyms: |
HR6B; UBC2; HHR6B; RAD6B; E2-17kDa |
Swissprot: |
P63146 |
Gene Accession: |
BC005979 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. |