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  • ZCCHC9 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW6630
    • 應用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:20
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中文名稱: ZCCHC9 抗原(重組蛋白)

英文名稱: ZCCHC9 Antigen (Recombinant Protein)

別     名: zinc finger, CCHC domain containing 9; PPP1R41

儲     存: 冷凍(-20℃)

相關(guān)類別:抗原

概     述

Fusion protein corresponding to C terminal 200 amino acids of human ZCCHC9

技術(shù)規(guī)格

Full name:

zinc finger, CCHC domain containing 9

Synonyms:

PPP1R41

Swissprot:

Q8N567

Gene Accession:

BC032736

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZCCHC9 (zinc finger, CCHC domain containing 9) is a 271 amino acid protein that contains four CCHC-type zinc finger, suggesting a role in transcriptional regulation. The gene encoding ZCCHC9 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.