兔抗H2AC4多克隆抗體

Background:

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]

Applications:

ELISA, WB, IHC

Name of antibody:

H2AC4

Immunogen:

Synthetic peptide of human H2AC4

Full name:

H2A clustered histone 4

Synonyms:

H2A/m; H2AFM; HIST1H2AB

SwissProt:

P04908

IHC positive control:

Human gasrtic cancer and Human thyroid cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

14 kDa

WB Positive control:

Hela, 231 and K562 cells,human fetal brain tissue

WB Recommended dilution:

200-1000