兔抗KCNE1多克隆抗體

Background:

Voltage-gated potassium channels play a variety of important roles in human health and disease. KCNE1, also known as MinK, belongs to a family of small transmembrane proteins (KCNE1, 2, 3, 4, and KCNE1L) that modulate the activity of several voltage-gated K+ channels. KCNE1 functions as the modulatory β-subunit of the pore-forming α-subunit KCNQ1, and alters several biophysical properties of KCNQ1 channels. Research studies have shown that several inherited mutations in KCNE1 result in long QT syndrome and deafness.

Applications:

WB

Name of antibody:

KCNE1

Immunogen:

Fusion protein of human KCNE1

Full name:

potassium voltage-gated channel, Isk-related family, member 1

Synonyms：

KCNE1; FLJ18426; FLJ38123; FLJ94103; ISK; JLNS; JLNS2; LQT2/5; LQT5; MGC33114; MinK

SwissProt:

P15382

WB Predicted band size:

15 kDa

WB Positive control:

Mouse heart and testis tissue

WB Recommended dilution:

500-2000