小鼠抗HSP90AA1單克隆抗體

Background:

HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding,protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress.There are 2 major cytosolic HSP90 proteins, HSP90AA1, an inducible form, and HSP90AB1 (MIM 140572), a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria

Applications:

WB

Name of antibody:

HSP90AA1

Immunogen:

Fusion protein of human HSP90AA1

Full name:

heat shock protein 90kDa alpha (cytosolic), class A member 1 (HSP90AA1), transcript variant 2

Synonyms:

EL52; HSP86; Hsp89; HSP89A; Hsp90; HSP90A; HSP90N; HSPC1; HSPCA; HSPCAL1; HSPCAL4; HSPN; LAP-2; LAP2

SwissProt:

P07900

WB Predicted band size:

85 kDa

WB Positive control:

Hela, SVT2, A549, COS7, Jurkat, MDCK, MCF-7 cell lysates

WB Recommended dilution:

500-2000