中文名稱:L3MBTL2抗原(重組蛋白)
英文名稱: L3MBTL2 Antigen (Recombinant Protein)
別 名: L3MBT; H-l(3)mbt-l
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 506-705 amino acids of human L3MBTL2 |
Full name: |
L3MBTL2, polycomb repressive complex 1 subunit |
Synonyms: |
L3MBT; H-l(3)mbt-l |
Swissprot: |
Q969R5 |
Gene Accession: |
BC017191 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'. |