中文名稱:VANGL1 抗原(重組蛋白)
英文名稱: VANGL1 Antigen (Recombinant Protein)
別 名: VANGL planar cell polarity protein 1; LPP2; STB2; STBM2; KITENIN
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 248-524 amino acids of human VANGL1 |
Full name: |
VANGL planar cell polarity protein 1 |
Synonyms: |
LPP2; STB2; STBM2; KITENIN |
Swissprot: |
Q8TAA9 |
Gene Accession: |
BC065272 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the tretraspanin family. The encoded protein may be involved in mediating intestinal trefoil factor induced wound healing in the intestinal mucosa. Mutations in this gene are associated with neural tube defects. Alternate splicing results in multiple transcript variants. Interacts through its C-terminal region with the N-terminal half of DVL1, DVL2 and DVL3. The PDZ domain of DVL1, DVL2 and DVL3 is required for the interaction. |