中文名稱(chēng):ALDH6A1 抗原(重組蛋白)
英文名稱(chēng): ALDH6A1 Antigen (Recombinant Protein)
別 名: aldehyde dehydrogenase 6 family, member A1; MMSDH; MMSADHA
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類(lèi)別: 抗原
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human ALDH6A1 |
Full name: |
aldehyde dehydrogenase 6 family, member A1 |
Synonyms: |
MMSDH; MMSADHA |
Swissprot: |
Q02252 |
Gene Accession: |
BC004909 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. |