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  • ANKMY2 抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號 : TW15936
    • 應用 : 僅限于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱：ANKMY2 抗原（重組蛋白）

英文名稱： ANKMY2 Antigen (Recombinant Protein)

別      名： ankyrin repeat and MYND domain containing 2; ZMYND20

儲      存： 冷凍（-20℃）

相關類別： 抗原

概  述：

Fusion protein corresponding to N terminal 320 amino acids of human ANKMY2


技術規(guī)格：

Full name:

ankyrin repeat and MYND domain containing 2

Synonyms:

ZMYND20

Swissprot:

Q8IV38

Gene Accession:

BC035353

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states.