中文名稱:ATF4抗原(重組蛋白)
英文名稱:ATF4 Antigen (Recombinant Protein)
儲(chǔ) 存:冷凍(-20℃)
相關(guān)類別:抗原
概述
Fusion protein corresponding to N terminal 300 amino acids of human ATF4 |
技術(shù)規(guī)格
Full name: |
activating transcription factor 4 |
Synonyms: |
CREB2; TXREB; CREB-2; TAXREB67 |
Swissprot: |
P18848 |
Gene Accession: |
BC008090 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. |