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細(xì)胞系

細(xì)胞庫(kù)

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原代細(xì)胞

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菌株

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科研抗體

ACVR2A 抗原（重組蛋白）

規(guī)格：

數(shù)量：

購(gòu)買數(shù)量

價(jià)格：￥

中文名稱：ACVR2A 抗原（重組蛋白）

英文名稱： ACVR2A Antigen (Recombinant Protein)

別名： Activin A receptor, type IIA; ACVR2; ACTRII

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to a region derived from 195-485 amino acids of human ACVR2A

技術(shù)規(guī)格：

Full name:	Activin A receptor, type IIA
Synonyms:	ACVR2; ACTRII
Swissprot:	P27037
Gene Accession:	BC069707
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.

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