小鼠抗RLIM單克隆抗體

Background:

The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Applications:

WB, IHC

Name of antibody:

RLIM

Immunogen:

Fusion protein of human RLIM

Full name:

ring finger protein, LIM domain interacting

Synonyms:

MRX61; RNF12; NY-REN-43

SwissProt:

Q9NVW2

IHC positive control:

Human liver tissue

IHC Recommend dilution:

200-500

WB Predicted band size:

69 KD

WB Positive control:

HepG2, Hela, A549 cell lysates

WB Recommended dilution:

500-2000