技術(shù)規(guī)格
Background: |
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Applications: |
WB |
Name of antibody: |
IL4 |
Immunogen: |
Synthesized peptide derived from C-terminal of human IL4. |
Full name: |
interleukin 4 |
Synonyms: |
BSF1; IL-4; BCGF1; BSF-1; BCGF-1 |
SwissProt: |
P05112 |
WB Predicted band size: |
17 kDa |
WB Positive control: |
Hela cells lysate |
WB Recommended dilution: |
500-3000 |
