抗 原: HDAC6(Phospho-Ser22)
標 記 物: Unconjugate
Background: |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. |
Applications: |
WB |
Name of antibody: |
HDAC6(Phospho-Ser22) |
Immunogen: |
Peptide sequence around phosphorylation site of serine 22 (P-Q-S(p)-P-P) derived from Human HDAC6. |
Full name: |
histone deacetylase 6 |
Synonyms: |
HD6; JM21; CPBHM; PPP1R90 |
SwissProt: |
Q9UBN7 |
WB Predicted band size: |
131 kDa |
WB Positive control: |
NIH/3T3 cells lysates |
WB Recommended dilution: |
500-1000 |