購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)：小鼠抗IDH2單克隆抗體
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Background: |
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. |
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Applications: |
ELISA, WB |
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Name of antibody: |
IDH2 |
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Immunogen: |
Fusion protein of human IDH2 |
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Full name: |
isocitrate dehydrogenase (NADP(+)) 2, mitochondrial |
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Synonyms: |
IDH; IDP; IDHM; IDPM; ICD-M; D2HGA2; mNADP-IDH |
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SwissProt: |
P48735 |
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WB Predicted band size: |
51 kDa |
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WB Positive control: |
HepG2 whole cell lysate |
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WB Recommended dilution: |
500-2000 |
