購(gòu)物車(chē)
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021-54845833/15800441009
中文名稱(chēng)： 兔抗ABL1/ABL2 (phospho-Tyr393/439)多克隆抗體
英文名稱(chēng)： Anti-ABL1/ABL2 (phospho-Tyr393/439) rabbit polyclonal antibody
別 名： Abelson murine leukemia viral oncogene homolog 1; c-ABL; p150
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃） 避光
宿 主： Rabbit
抗 原： ABL1/ABL2(phospho-Tyr393/439)
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks. |
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Applications: |
WB, IHC, IF |
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Name of antibody: |
ABL1/ABL2(phospho-Tyr393/439) |
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Immunogen: |
Peptide sequence around phosphorylation site of tyrosine 393/439 (D-T-Y(p)-T-A) derived from Human ABL1/2. |
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Full name: |
ABL proto-oncogene 1, non-receptor tyrosine kinase/ABL proto-oncogene 2, non-receptor tyrosine kinase |
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Synonyms: |
ABL; JTK7; p150; c-ABL; v-abl; CHDSKM; c-ABL1; bcr/abl; ARG; ABLL |
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SwissProt: |
P00519/P42684 |
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IHC positive control: |
Human breast carcinoma |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
210 kDa |
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WB Positive control: |
HL60 cells |
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WB Recommended dilution: |
500-1000 |
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IF Positive control: |
Hela cells |
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IF Recommended dilution: |
100-200 |
