中文名稱: ZKSCAN3 抗原(重組蛋白)
英文名稱: ZKSCAN3 Antigen (Recombinant Protein)
別 名: zinc finger with KRAB and SCAN domains 3; ZF47; Zfp47; ZFP306; ZNF306; ZNF309; zfp-47; ZSCAN13; ZSCAN35; dJ874C20.1; dJ874C20.1.
相關(guān)類別: 抗原
儲(chǔ) 存: 冷凍(-20℃)
概 述
Full name: |
zinc finger with KRAB and SCAN domains 3 |
Synonyms: |
ZF47; Zfp47; ZFP306; ZNF306; ZNF309; zfp-47; ZSCAN13; ZSCAN35; dJ874C20.1; dJ874C20.1. |
Swissprot: |
Q9BRR0 |
Gene Accession: |
BC006118 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas. |