歡迎來(lái)到上海通蔚！

021-54845833/15800441009

品質(zhì)保證 · 通蔚試劑

當(dāng)前位置: 首頁(yè) > 科研產(chǎn)品 > 科研抗體 > 其他抗體 > ZC3H7A抗原（重組蛋白）

產(chǎn)品中心

  • ZC3H7A抗原（重組蛋白）

    規(guī)格：
    數(shù)量：

    購(gòu)買數(shù)量

    價(jià)格：￥
    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW6622
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存：20
  • 商品詳情
  • 參考文獻(xiàn)
  • 說(shuō)明書(shū)下載
  • 商品評(píng)論0
  • 相關(guān)產(chǎn)品

中文名稱：ZC3H7A抗原（重組蛋白）

英文名稱： ZC3H7A Antigen (Recombinant Protein)

別     名： ZC3H7; HSPC055; ZC3HDC7

儲(chǔ)     存： 冷凍（-20℃）

相關(guān)類別：抗原

概     述

Fusion protein corresponding to a region derived from 805-971 amino acids of human ZC3H7A

技術(shù)規(guī)格

Full name:

zinc finger CCCH-type containing 7A

Synonyms:

ZC3H7; HSPC055; ZC3HDC7

Swissprot:

Q8IWR0

Gene Accession:

BC012575

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The zinc finger CCCH domain-containing protein 7A (ZC3H7A), also known as ZC3H7, HSPC055 or ZC3HDC7, is a 971 amino acid protein that contains a C3H1-type zinc finger domain, three C3H1-type zinc fingers and three TPR repeats. Belonging to the ZC3H12 family, ZC3H7A localizes to the nucleus. Existing as two alternatively spliced isoforms, ZC3H7A is encoded by a gene located on human chromosome 16p13.13. Chromosome 16 makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.