小鼠抗CCT5單克隆抗體

Background:

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13.

Applications:

ELISA, WB

Name of antibody:

CCT5

Immunogen:

Fusion protein of human CCT5

Full name:

chaperonin containing TCP1 subunit 5

Synonyms:

CCTE; HEL-S-69; PNAS-102; CCT-epsilon; TCP-1-epsilon

SwissProt:

P48643

WB Predicted band size:

60 kDa

WB Positive control:

SW480 whole cell lysate

WB Recommended dilution:

500-2000