VSX1 抗原（重組蛋白）

Full name:

visual system homeobox 1

Synonyms:

PPD; KTCN; PPCD; RINX; KTCN1; PPCD1; CAASDS

Swissprot:

Q9NZR4

Gene Accession:

BC126228

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described.