購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： 兔抗ADAMTS2多克隆抗體
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Background: |
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase. This proteinase excises the N-propeptide of the fibrillar procollagens types I-III and type V. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
ADAMTS2 |
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Immunogen: |
Synthetic peptide of human ADAMTS2 |
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Full name: |
ADAM metallopeptidase with thrombospondin type 1 motif 2 |
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Synonyms: |
NPI; PNPI; PCINP; PCPNI; PCI-NP; PC I-NP; ADAM-TS2; ADAMTS-2; ADAMTS-3; EDSDERMS |
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SwissProt: |
O95450 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil and Human colorectal cancer |
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IHC Recommend dilution: |
30-150 |
