UGT2B4 抗原（重組蛋白）

Full name:

UDP glucuronosyltransferase 2 family, polypeptide B4

Synonyms:

HLUG25; UDPGTH1; UGT2B11; UDPGT2B4; UDPGTh-1

Swissprot:

P06133

Gene Accession:

BC026264

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.