中文名稱: TRIM27 抗原(重組蛋白)
英文名稱: TRIM27 Antigen (Recombinant Protein)
別 名: tripartite motif containing 27; RFP; RNF76
儲 存: 冷凍(-20℃)
相關(guān)類別:抗原
概 述
Full name: |
tripartite motif containing 27 |
Synonyms: |
RFP; RNF76 |
Swissprot: |
P14373 |
Gene Accession: |
BC013580 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein. |