中文名稱: STAG2 抗原(重組蛋白)
英文名稱: STAG2 Antigen (Recombinant Protein)
別 名: stromal antigen 2; SA2; SA-2; SCC3B; bA517O1.1
儲 存: 冷凍(-20℃)
相關(guān)類別:抗原
概 述
技術(shù)規(guī)格
Full name: |
stromal antigen 2 |
Synonyms: |
SA2; SA-2; SCC3B; bA517O1.1 |
Swissprot: |
Q8N3U4 |
Gene Accession: |
BC001765 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a subunit of the cohesin complex, which regulates the separation of sister chromatids during cell division. Targeted inactivation of this gene results in chromatid cohesion defects and aneuploidy, suggesting that genetic disruption of cohesin is a cause of aneuploidy in human cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |