兔抗CD3D多克隆抗體

Background:

The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.

Applications:

WB

Name of antibody:

CD3D

Immunogen:

Fusion protein of human CD3D

Full name:

CD3d molecule, delta (CD3-TCR complex)

Synonyms：

CD3D; CD3-DELTA; T3

SwissProt:

P04234

WB Predicted band size:

19 kDa

WB Positive control:

Jurkat and HuT-78 cells

WB Recommended dilution:

500-2000