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中文名稱：兔抗CCNC(Ab-275)多克隆抗體
英文名稱： Anti-CCNC(Ab-275) rabbit polyclonal antibody
別 名： CycC
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃） 避光
抗 原： CCNC(Ab-275)
宿 主： Rabbit
標(biāo) 記 物： Unconjugate
克隆類型： Unconjugate
技術(shù)規(guī)格
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Background: |
Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex. |
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Applications: |
WB |
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Name of antibody: |
CCNC(Ab-275) |
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Immunogen: |
Synthesized non-phosphopeptide derived from human Cyclin C around the phosphorylation site of serine 275 (N-G-S(p)-Q-N). |
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Full name: |
cyclin C |
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Synonyms： |
CycC |
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SwissProt: |
P24863 |
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WB Predicted band size: |
33 kDa |
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WB Positive control: |
LOVO cells lysate |
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WB Recommended dilution: |
500-3000 |
