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中文名稱(chēng): RGS1 抗原(重組蛋白)

英文名稱(chēng): RGS1 Antigen (Recombinant Protein)

別      名: regulator of G-protein signaling 1; 1R20; BL34; IER1; IR20; HEL-S-87

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類(lèi)別:抗原

概      述

Fusion protein corresponding to N terminal 141 amino acids of human RGS1

技術(shù)規(guī)格

Full name:

regulator of G-protein signaling 1

Synonyms:

1R20; BL34; IER1; IR20; HEL-S-87

Swissprot:

Q08116

Gene Accession:

BC015510

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.