中文名稱:兔抗CARD8多克隆抗體
英文名稱: Anti-CARD8 rabbit polyclonal antibody
別 名: CARD8; CARDINAL; DACAR; DKFZp779L0366; Dakar; FLJ18119; FLJ18121; KIAA0955; MGC57162; NDPP; NDPP1; TUCAN
相關(guān)類別: 一抗
抗 原: CARD8
儲 存: 冷凍(-20℃) 避光
宿 主: Rabbit
反應(yīng)種屬: Human
標 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. |
Applications: |
WB |
Name of antibody: |
CARD8 |
Immunogen: |
Fusion protein of human CARD8 |
Full name: |
Caspase recruitment domain-containing protein 8 |
Synonyms: |
CARD8; CARDINAL; DACAR; DKFZp779L0366; Dakar; FLJ18119; FLJ18121; KIAA0955; MGC57162; NDPP; NDPP1; TUCAN |
SwissProt: |
Q9Y2G2 |
WB Predicted band size: |
49 kDa |
WB Positive control: |
K562 and Hela cells |
WB Recommended dilution: |
500-2000 |