兔抗C3/C3b多克隆抗體

Background:

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.

Applications:

ELISA, IHC

Name of antibody:

C3/C3b

Immunogen:

Synthetic peptide of human C3/C3b

Full name:

complement component 3

Synonyms:

ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p

SwissProt:

P01024

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

20-100