Background: |
SRPX gene also designated ETX1, resides within this region and is deleted in XLRP patients. There are at least two splice variants of SRPX, one of which contains a thirty amino acid signal peptide. Both variants contain three complement control protein domains, a hydrophobic region for membrane anchorage, and a cytoplasmic carboxy terminus. SRPX is expressed in retina and heart. SRPX is highly homologous to the drs (downregulated by v-src) human homolog, which suggests a role for SRPX as a tumor suppressor. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
SRPX |
Immunogen: |
Fusion protein of human SRPX |
Full name: |
sushi-repeat containing protein, X-linked |
Synonyms: |
DRS; ETX1; SRPX1; HEL-S-83p |
SwissProt: |
P78539 |
ELISA Recommended dilution: |
2000-10000 |
IHC positive control: |
Human prostate cancer and Human brain |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
52 kDa |
WB Positive control: |
293T cells |
WB Recommended dilution: |
1000-5000 |