中文名稱: 兔抗TRIB2多克隆抗體
英文名稱: Anti-TRIB2 rabbit polyclonal antibody
別 名: C5FW; TRB2; GS3955
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: TRIB2
反應(yīng)種屬: Human, Mouse
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. |
Applications: |
ELISA, IHC |
Name of antibody: |
TRIB2 |
Immunogen: |
Full length fusion protein |
Full name: |
tribbles pseudokinase 2 |
Synonyms: |
C5FW; TRB2; GS3955 |
SwissProt: |
Q92519 |
ELISA Recommended dilution: |
2000-10000 |
IHC positive control: |
Human gastric cancer |
IHC Recommend dilution: |
30-150 |