中文名稱: 兔抗PTPN2多克隆抗體
英文名稱: Anti-PTPN2 rabbit polyclonal antibody
別 名: PTN2; PTPT; TCPTP; TC-PTP; TCELLPTP
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃) 避光
宿 主: Rabbit
抗 原: PTPN2
反應(yīng)種屬: Human, Mouse, Rat
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. |
Applications: |
WB |
Name of antibody: |
PTPN2 |
Immunogen: |
Fusion protein of human PTPN2 |
Full name: |
protein tyrosine phosphatase, non-receptor type 2 |
Synonyms: |
PTN2; PTPT; TCPTP; TC-PTP; TCELLPTP |
SwissProt: |
P17706 |
WB Predicted band size: |
49 kDa |
WB Positive control: |
SW680, BT474, Jurkat and K562 cells |
WB Recommended dilution: |
500-2000 |