兔抗PSMA3多克隆抗體

Background:

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.

Applications:

ELISA, WB, IHC

Name of antibody:

PSMA3

Immunogen:

Fusion protein of human PSMA3

Full name:

proteasome subunit alpha 3

Synonyms:

HC8; PSC3

SwissProt:

P25788

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human ovarian cancer and Human thyroid cancer

IHC Recommend dilution:

40-200

WB Predicted band size:

28 kDa

WB Positive control:

NIH/3T3, A549, HL60 and PC3 cell, Mouse liver tissue, Mouse spleen tissue, Hela cell lysates

WB Recommended dilution:

500-2000