購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)： 兔抗PRMT6多克隆抗體
英文名稱(chēng)： Anti-PRMT6 rabbit polyclonal antibody
別 名： protein arginine methyltransferase 6; HRMT1L6
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： PRMT6
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
PRMT6 |
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Immunogen: |
Synthetic peptide of human PRMT6 |
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Full name: |
protein arginine methyltransferase 6 |
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Synonyms: |
HRMT1L6 |
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SwissProt: |
Q96LA8 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human ovarian cancer |
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IHC Recommend dilution: |
20-100 |
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WB Predicted band size: |
42 kDa |
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WB Positive control: |
NIH/3T3 and 293T cell lysates |
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WB Recommended dilution: |
200-1000 |
