兔抗PIDD1多克隆抗體

Background:

The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis.

Applications:

ELISA, IHC

Name of antibody:

PIDD1

Immunogen:

Fusion protein of human PIDD1

Full name:

p53-induced death domain protein 1

Synonyms：

LRDD; PIDD

SwissProt:

Q9HB75

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and human brain

IHC Recommend dilution:

50-200