兔抗NRG2多克隆抗體

Background:

This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described.

Applications:

ELISA, IHC

Name of antibody:

NRG2

Immunogen:

Synthetic peptide of human NRG2

Full name:

neuregulin 2

Synonyms:

DON1; HRG2; NTAK

SwissProt:

O14511

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and human liver cancer

IHC Recommend dilution:

20-100